1501 N. Campbell Ave. COM Room 8403
Tucson, AZ. 85724
Endocrinology, Diabetes & Metabolism Grand Rounds
Stevan P. Tofovic, MD, PhD, FAHA, FASN, Associate Professor of Medicine, Division of Pulmonary, Allergy & Critical Care, Department of Medicine, at the University of Pittsburgh School of Medicine.
Dr. Tofovic is interested in the development and characterization of complex animal models of cardiovascular and renal disease, with primary focus on pulmonary hypertension, heart failure and diabetic nephropathy. He has developed and characterized the obese diabetic ZSF1 rat as a model of diabetic nephropathy and heart failure with preserved ejection fraction (HFpEF).
Dr. Tofovic’s lab is one of the few laboratories in the country that is studying the effects of gender and estradiol metabolism on the development and progression of pulmonary hypertension. More recent studies are related to (1) the effects of sex and sex hormones and their metabolites on development of HFpEF and (2) the role of adenosine metabolom and adenosine-adenosine demainase axis in PH with focus on hemolysis-induced hemolytic pulmonary vasculopathy.
TOPIC: "Effects of Sex and Estradiol Metabolites on Cardiovascular and Renal Disease in Rat Models of Metabolic Syndrome".